![Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes | Nature Neuroscience Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes | Nature Neuroscience](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41593-018-0075-7/MediaObjects/41593_2018_75_Fig1_HTML.gif)
Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes | Nature Neuroscience
![Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders | Science Advances Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders | Science Advances](https://www.science.org/cms/10.1126/sciadv.abn4704/asset/d7fc7239-69c2-4ba6-8ed1-3067560a3e23/assets/images/large/sciadv.abn4704-f1.jpg)
Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders | Science Advances
![In Vivo Pharmacodynamic Method to Assess Complement C5a Receptor Antagonist Efficacy | ACS Pharmacology & Translational Science In Vivo Pharmacodynamic Method to Assess Complement C5a Receptor Antagonist Efficacy | ACS Pharmacology & Translational Science](https://pubs.acs.org/cms/10.1021/acsptsci.1c00227/asset/images/large/pt1c00227_0007.jpeg)
In Vivo Pharmacodynamic Method to Assess Complement C5a Receptor Antagonist Efficacy | ACS Pharmacology & Translational Science
![Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation: Cell Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation: Cell](https://www.cell.com/cms/attachment/2092275394/2076488139/gr1.jpg)
Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation: Cell
![Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties | Nature Communications Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-021-26684-z/MediaObjects/41467_2021_26684_Fig1_HTML.png)
Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties | Nature Communications
![Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease | Nature Communications Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-021-25651-y/MediaObjects/41467_2021_25651_Fig1_HTML.png)
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease | Nature Communications
![De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids, and in Vivo | ACS Nano De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids, and in Vivo | ACS Nano](https://pubs.acs.org/cms/10.1021/acsnano.9b08011/asset/images/medium/nn9b08011_0010.gif)
De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids, and in Vivo | ACS Nano
![Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation - ScienceDirect Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S089662732030475X-fx1.jpg)